AS1842856, CAS [[836620-48-5]]

Product Overview

• Article Name: AS1842856, CAS [[836620-48-5]]
• Biozol Catalog Number: FBM-10-5344
• Supplier Catalog Number: 10-5344
• Alternative Catalog Number: FBM-10-5344-5MG, FBM-10-5344-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-Amino-7-(cyclohexylamino)-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Product Description

FOXO1 inhibitor

Product Properties

• Molecular Weight: 347.39
• Purity: >98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [836620-48-5]
• Formula: C18H22FN3O3

Application Notes

• Application Notes: AS1842856 is a potent and selective FOXO1 inhibitor, IC50s=33 nM and >1 mM for FOXO3a and 4.1 Oral administration to diabetic db/db mice leads to a reduction of fasting plasma glucose levels.1 Suppresses autophagy, FSP27 expression and adipocyte differentiation.2 AS1842856 is a highly useful tool for probing the involvement of FOXO1 in cellular processes.3-5