CID1067700, CAS [[314042-01-8]]

Product Overview

• Article Name: CID1067700, CAS [[314042-01-8]]
• Biozol Catalog Number: FBM-10-5401
• Supplier Catalog Number: 10-5401
• Alternative Catalog Number: FBM-10-5401-5MG, FBM-10-5401-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-[[(benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid. Alternate Names: ML282

Product Description

Rab7 GTPase inhibitor

Product Properties

• Molecular Weight: 390.48
• Purity: 98% by TLC NMR (Conforms)
• Form: White solid
• CAS Number: [314042-01-8]
• Formula: C18H18N2O4S2

Application Notes

• Application Notes: A specific competitive inhibitor of nucleotide binding to Rab7, an endosome-localized small GTPase.1 It interferes with the Rab7-RILP interaction, locking the GTPase in an inactive conformation.2 Impairs B cell class switching and plasma cell survival dampening, the pathogenic autoantibody response in lupus.3 Inhibits the Arf-like small GTPase Arl8b, blocking cellular egress of b-coronaviruses (SARS-CoV-2) which utilize a lysosomal exocytosis pathway.4