BG45, CAS [[926259-99-6]]

Product Overview

• Article Name: BG45, CAS [[926259-99-6]]
• Biozol Catalog Number: FBM-10-5638
• Supplier Catalog Number: 10-5638
• Alternative Catalog Number: FBM-10-5638-5MG, FBM-10-5638-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(2-Aminophenyl)-2-pyrazinecarboxamide

Product Description

HDAC3 selective inhibitor

Product Properties

• Molecular Weight: 214.23
• Purity: >98% by HPLC NMR (Conforms)
• Form: Beige solid
• CAS Number: [926259-99-6]
• Formula: C11H10N4O

Application Notes

• Application Notes: Potent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 mM respectively.1 Inhibits tumor growth in a mouse xenograft model of human multiple myeloma.1 Downregulates expression of DNA methyltransferase 1.2 Increases expression of synaptic proteins in exogenous Abeta-treated cells and mice.3 Rescues synaptic damage and neuron loss in APP-transfected cells (15 mM) and APP/PS1 mice (30 mg/kg).4