PF-2545920, CAS [[898562-94-2]]

Catalog Number: FBM-10-5804
Article Name: PF-2545920, CAS [[898562-94-2]]
Biozol Catalog Number: FBM-10-5804
Supplier Catalog Number: 10-5804
Alternative Catalog Number: FBM-10-5804-5MG, FBM-10-5804-25MG
Manufacturer: Focus Biomolecules
Category: Biochemikalien
Alternative Names: Chemical Name: 2-[[4-[1-Methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-quinoline. Alternate Names: MP-10, PF-920, Mardepodect
PDE10A inhibitor
Molecular Weight: 392.46
Purity: >98% by HPLC NMR (Conforms)
Form: Off-white solid
CAS Number: [898562-94-2]
Formula: C25H20N4O
Application Notes: PF-2545920 is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), IC50 = 0.37 nM.1 Active in a number of animal models for antipsychotic activity.2 Suppresses microglial activation in LPA-induced neuroinflammation and MPTP-induced Parkinsons disease models.3 Suppresses proliferation of human glioblastoma cells.4 Novel agent for stimulation of sperm motility.5 Brain penetrant.