Chemical Name: 2-[[4-[1-Methyl-4-(4-pyridinyl)-1H-pyrazol-3-yl]phenoxy]methyl]-quinoline. Alternate Names: MP-10, PF-920, Mardepodect
PDE10A inhibitor
Molecular Weight:
392.46
Purity:
>98% by HPLC NMR (Conforms)
Form:
Off-white solid
CAS Number:
[898562-94-2]
Formula:
C25H20N4O
Application Notes:
PF-2545920 is a potent and selective inhibitor of phosphodiesterase 10A (PDE10A), IC50 = 0.37 nM.1 Active in a number of animal models for antipsychotic activity.2 Suppresses microglial activation in LPA-induced neuroinflammation and MPTP-induced Parkinsons disease models.3 Suppresses proliferation of human glioblastoma cells.4 Novel agent for stimulation of sperm motility.5 Brain penetrant.
* VAT and and shipping costs not included. Errors and price changes excepted