Tat- betasyn-degron

Product Overview

• Article Name: Tat- betasyn-degron
• Biozol Catalog Number: ISC-PP-040
• Supplier Catalog Number: PP-040
• Alternative Catalog Number: ISC-PP-040
• Manufacturer: Isca Biochemicals
• Category: Biochemikalien
• Alternative Names: Tat- betasyn-degron peptide

Product Description

Tat- betasyn-degron is a blood brain barrier and plasma membrane permeable alpha-synuclein knockdown peptide which can reduce the level of alpha-synuclein by proteasomal degradation. Tat- betasyn-degron decreases alpha-synuclein aggregates and microglial activation in an alpha-synuclein preformed fibril model of spreading synucleinopathy in transgenic mice overexpressing human A53T alpha-synuclein, and reduces alpha-synuclein levels and significantly decreases the neuronal damage and motor impairment in a mouse toxicity model of Parkinsons disease.

Product Properties

• Molecular Weight: 3146.71
• NCBI: 2021
• Purity: >95% by hplc
• Form: Freeze fried solid
• Sequence: H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Arg-Thr-Lys-Ser-Gly-Val-Tyr-Leu-Val-Gly-Arg-Arg-Arg-Gly-OH
• Formula: C132H237N59O31
• Target: Protein-protein interactions,Proteasome

Application Notes

• Application Notes: ProductType: Cell penetrating peptides