Nevanimibe hydrochloride (PD-132301 hydrochloride) is an orally active and selective acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) inhibitor with an EC50 of 9 nM. Nevanimibe hydrochloride inhibits ACAT2 with an EC50 of 368 nM. Nevanimibe hydrochloride induces cell apoptosis and has the potential for adrenocortical cancer[1].
Molecular Weight:
458.08
Purity:
99.49
CAS Number:
[133825-81-7]
Formula:
C27H40ClN3O
Target:
Acyltransferase,Apoptosis
Application Notes:
Reference compound
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