TAK-243, CAS [[1450833-55-2]]

Product Overview

• Article Name: TAK-243, CAS [[1450833-55-2]]
• Biozol Catalog Number: MCE-HY-100487
• Supplier Catalog Number: HY-100487
• Alternative Catalog Number: MCE-HY-100487-100MG,MCE-HY-100487-5MG,MCE-HY-100487-10MG,MCE-HY-100487-10MMX1ML,MCE-HY-100487-25MG,MCE-HY-100487-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: MLN7243

Product Description

TAK-243 (MLN7243) is a first-in-class, selective ubiquitin activating enzyme, UAE (UBA1) inhibitor (IC50=1 nM), which blocks ubiquitin conjugation, disrupting monoubiquitin signaling as well as global protein ubiquitination. TAK-243 (MLN7243) induces endoplasmic reticulum (ER) stress, abrogates NF-kappaB pathway activation and promotes apoptosis[1][2].

Product Properties

• Molecular Weight: 519.52
• Purity: 98.38
• CAS Number: [1450833-55-2]
• Formula: C19H20F3N5O5S2
• Target: Apoptosis,E1/E2/E3 Enzyme,NF-kappaB

Application Notes

• Application Notes: MCE Product type: Reference compound