Landiolol (hydrochloride), CAS [[144481-98-1]]

Product Overview

• Article Name: Landiolol (hydrochloride), CAS [[144481-98-1]]
• Biozol Catalog Number: MCE-HY-100607A
• Supplier Catalog Number: HY-100607A
• Alternative Catalog Number: MCE-HY-100607A-10MG,MCE-HY-100607A-10MMX1ML,MCE-HY-100607A-100MG,MCE-HY-100607A-25MG,MCE-HY-100607A-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: ONO1101 (hydrochloride)

Product Description

Landiolol (ONO1101) hydrochloride is a highly selective, ultra-short-acting competitive inhibitor of beta1 adrenergic receptors. Landiolol hydrochloride specifically blocks cardiac beta1 receptors, reducing heart rate and myocardial oxygen consumption. Landiolol hydrochloride inhibits TNF-alpha-induced excessive mitochondrial oxygen consumption and reactive oxygen species production in a sepsis model, alleviating renal injury. Landiolol hydrochloride has little effect on cardiac ion channels (such as L-type calcium current and inward rectifier potassium current) and has a weak negative inotropic effect. Landiolol hydrochloride can be used for perioperative tachycardia control and protection studies of sepsis-related acute kidney injury[1][2][3].

Product Properties

• Molecular Weight: 546.05
• Purity: 99.96
• CAS Number: [144481-98-1]
• Formula: C25H40ClN3O8
• Target: Adrenergic Receptor,Calcium Channel,Potassium Channel,Reactive Oxygen Species (ROS)

Application Notes

• Application Notes: MCE Product type: Reference compound