IC 86621, CAS [[404009-40-1]]

Product Overview

• Article Name: IC 86621, CAS [[404009-40-1]]
• Biozol Catalog Number: MCE-HY-100707
• Supplier Catalog Number: HY-100707
• Alternative Catalog Number: MCE-HY-100707-5MG,MCE-HY-100707-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

IC 86621 is a potent DNA-dependent protein kinase (DNA-PK) inhibitor, with an IC50 of 120 nM. IC 86621 also acts as a selective and reversible ATP-competitive inhibitor.IC 86621 inhibits DNA-PK mediated cellular DNA double-strand break (DSB) repair (EC50=68 µM). IC 86621 increases DSB-induced antitumor activity without cytotoxic effects. IC 86621 can protects rheumatoid arthritis (RA) T cells from apoptosis[1][2].

Product Properties

• Molecular Weight: 221.26
• Purity: 99.06
• CAS Number: [404009-40-1]
• Formula: C12H15NO3
• Target: Apoptosis,DNA-PK

Application Notes

• Application Notes: Reference compound