Laduviglusib (monohydrochloride), CAS [[1797989-42-4]]

Product Overview

• Article Name: Laduviglusib (monohydrochloride), CAS [[1797989-42-4]]
• Biozol Catalog Number: MCE-HY-10182A
• Supplier Catalog Number: HY-10182A
• Alternative Catalog Number: MCE-HY-10182A-5MG,MCE-HY-10182A-10MMX1ML,MCE-HY-10182A-10MG,MCE-HY-10182A-50MG,MCE-HY-10182A-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: CHIR-99021 (monohydrochloride), CT99021 (monohydrochloride)

Product Description

Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3alpha/beta inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/beta-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy[1][2][3].

Product Properties

• Molecular Weight: 501.80
• Purity: 99.93
• CAS Number: [1797989-42-4]
• Formula: C22H19Cl3N8
• Target: Autophagy,GSK-3,Organoid,Wnt,beta-catenin

Application Notes

• Application Notes: MCE Product type: Reference compound1