(S)-SNAP5114, CAS [[157604-55-2]]

Product Overview

• Article Name: (S)-SNAP5114, CAS [[157604-55-2]]
• Biozol Catalog Number: MCE-HY-103504
• Supplier Catalog Number: HY-103504
• Alternative Catalog Number: MCE-HY-103504-25MG,MCE-HY-103504-50MG,MCE-HY-103504-100MG,MCE-HY-103504-10MG,MCE-HY-103504-10MMX1ML,MCE-HY-103504-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(S)-SNAP5114 is a non-covalent murine GABA transporter inhibitor with blood-brain barrier penetration ability, which exhibits significant subtype-selective inhibitory activity against mGAT4 (pIC50=5.71, pKi=4.56), much higher than its effects on mGAT1, mGAT2 and mGAT3. (S)-SNAP5114 elevates extracellular GABA concentrations by blocking the GABA reuptake mechanism, thereby enhancing thalamus-specific GABAergic signaling and exerting potential neuromodulatory effects. (S)-SNAP5114 is widely used in studies related to epilepsy, neuropathic pain, anxiety and depression, and various neurodegenerative diseases[1][2][3].

Product Properties

• Molecular Weight: 505.60
• Purity: 98.09
• CAS Number: [157604-55-2]
• Formula: C30H35NO6
• Target: GABA Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound1