Officinalisinin I is a growth hormone receptor (GHR) ligand, hypoglycemic agent and neuroprotective agent. Officinalisinin I directly interacts with GHR and activates the JAK2-STAT5 signaling pathway. Officinalisinin I promotes the proliferation of lymphoma cells. Officinalisinin I promotes the production of GLP-1 and brain-derived neurotrophic factor (BDNF, enhances the activity of GSH-PX, reduces blood glucose and improves glucose tolerance. Officinalisinin I exerts a protective effect on diabetic nephropathy. Officinalisinin I can be used in studies related to diabetes and diabetic nephropathy[1][2].
Molecular Weight:
921.07
Purity:
99.89
CAS Number:
[57944-18-0]
Formula:
C45H76O19
Target:
GHR,GLP Receptor,Glutathione Peroxidase,JAK,STAT
Application Notes:
MCE Product type: Natural Products
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