YM-244769 (hydrochloride), CAS [[837424-39-2]]

Product Overview

• Article Name: YM-244769 (hydrochloride), CAS [[837424-39-2]]
• Biozol Catalog Number: MCE-HY-107659
• Supplier Catalog Number: HY-107659
• Alternative Catalog Number: MCE-HY-107659-10MG,MCE-HY-107659-50MG,MCE-HY-107659-25MG,MCE-HY-107659-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

YM-244769 hydrochloride is a potent, selective and orally active Na+/Ca2+ exchanger (NCX) inhibitor. YM-244769 hydrochloride preferentially inhibits NCX3 and suppresses the unidirectional outward NCX current (Ca2+ entry mode), with IC50s of 18 nM and 50 nM, respectively. YM-244769 hydrochloride efficiently protects against hypoxia/reoxygenation-induced SH-SY5Y neuronal cell damage. YM-244769 hydrochloride can also increase urine volume and urinary excretion of electrolytes in mice[1][2][3].

Product Properties

• Molecular Weight: 479.93
• Purity: 99.02
• CAS Number: [837424-39-2]
• Formula: C26H23ClFN3O3
• Target: Na+/Ca2+ Exchanger

Application Notes

• Application Notes: MCE Product type: Reference compound