Bisindolylmaleimide X (hydrochloride), CAS [[145317-11-9]]

Product Overview

• Article Name: Bisindolylmaleimide X (hydrochloride), CAS [[145317-11-9]]
• Biozol Catalog Number: MCE-HY-108136A
• Supplier Catalog Number: HY-108136A
• Alternative Catalog Number: MCE-HY-108136A-50MG,MCE-HY-108136A-10MG,MCE-HY-108136A-5MG,MCE-HY-108136A-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: BIM-X (hydrochloride), Ro31-8425 (hydrochloride)

Product Description

Bisindolylmaleimide X hydrochloride(Ro 31-8425 hydrochloride, BIM-X hydrochloride) is a cell-penetrating PKC inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM. Bisindolylmaleimide X hydrochloride inhibits the proliferation of CD4 T cells in vitro. Bisindolylmaleimide X hydrochloride inhibits eNOS-Ser1177 phosphorylation in human embryonic vein endothelial cells. Bisindolylmaleimide X hydrochloride can be used for research on the immune system and cardiovascular diseases[1][2][3].

Product Properties

• Molecular Weight: 460.96
• Purity: 98.90
• CAS Number: [145317-11-9]
• Formula: C26H25ClN4O2
• Target: CDK,PKC

Application Notes

• Application Notes: MCE Product type: Reference compound