GNE-781, CAS [[1936422-33-1]]

Product Overview

• Article Name: GNE-781, CAS [[1936422-33-1]]
• Biozol Catalog Number: MCE-HY-108696
• Supplier Catalog Number: HY-108696
• Alternative Catalog Number: MCE-HY-108696-50MG,MCE-HY-108696-5MG,MCE-HY-108696-10MG,MCE-HY-108696-100MG,MCE-HY-108696-25MG,MCE-HY-108696-1MG,MCE-HY-108696-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GNE-781 is an orally active, highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. GNE-781 displays antitumor activity in an MOLM-16 AML xenograft model[1].

Product Properties

• Molecular Weight: 525.59
• Purity: 98.16
• CAS Number: [1936422-33-1]
• Formula: C27H33F2N7O2
• Target: Epigenetic Reader Domain,Histone Acetyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound