(S)-PFI-2 (hydrochloride), CAS [[1627607-88-8]] Preis auf Anfrage

Product Overview

• Article Name: (S)-PFI-2 (hydrochloride), CAS [[1627607-88-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-110196
• Supplier Catalog Number: HY-110196
• Alternative Catalog Number: MCE-HY-110196-5MG,MCE-HY-110196-1MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

(S)-PFI-2 hydrochloride is an inhibitor of lysine methyltransferase SETD7 and is approximately 500-fold more active than its enantiomer (R)-PFI-2. (R)-PFI-2 is a cofactor-dependent and substrate-competitive inhibitor. (R)-PFI-2 can occupy the substrate peptide binding groove of SETD7 (including the catalytic lysine binding channel) and interact with the cofactor The donor methyl group is in direct contact. However, (S)-PFI-2 was not observed to have the same interaction as (R)-PFI-2[1][2].

Product Properties

• Molecular Weight: 535.98
• CAS Number: [1627607-88-8]
• Formula: C23H26ClF4N3O3S
• Target: Histone Methyltransferase

Application Notes

• Application Notes: MCE Product type: Reference compound