Tyk2-IN-5, CAS [[1797432-62-2]]

Product Overview

• Article Name: Tyk2-IN-5, CAS [[1797432-62-2]]
• Biozol Catalog Number: MCE-HY-111745
• Supplier Catalog Number: HY-111745
• Alternative Catalog Number: MCE-HY-111745-25MG,MCE-HY-111745-10MMX1ML,MCE-HY-111745-50MG,MCE-HY-111745-100MG,MCE-HY-111745-5MG,MCE-HY-111745-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Tyk2-IN-5 (compound 6) is a potent, selective and orally active tyrosine kinase 2 (Tyk2) inhibitor that acts on the JH2 structural domain. Tyk2-IN-5 shows a Ki value of 0.086 nM for Tyk2 JH2 and an IC50 value of 25 nM for IFNalpha. Tyk2-IN-5 efficiently inhibits the production of IFNgamma in a pharmacodynamic rat model and is fully efficacious in a rat model of arthritis[1].

Product Properties

• Molecular Weight: 434.43
• Purity: 99.35
• CAS Number: [1797432-62-2]
• Formula: C21H19FN8O2
• Target: JAK

Application Notes

• Application Notes: MCE Product type: Reference compound