JNJ-61432059 is a blood-brain barrier-permeable, orally active TARP gamma-8-associated AMPAR modulator with anticonvulsant activity. JNJ-61432059 negatively regulates GluA1 and positively modulates GluA2-containing AMPARs. JNJ-61432059 exerts potent protective effects in rodent epilepsy models. JNJ-61432059 is applicable for epilepsy-related research[1][2].
Molecular Weight:
443.47
Purity:
99.18
CAS Number:
[2035814-50-5]
Formula:
C25H22FN5O2
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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