PROTAC RAR Degrader-1, CAS [[1351169-27-1]]

Catalog Number: MCE-HY-111844
Article Name: PROTAC RAR Degrader-1, CAS [[1351169-27-1]]
Biozol Catalog Number: MCE-HY-111844
Supplier Catalog Number: HY-111844
Alternative Catalog Number: MCE-HY-111844-10MG,MCE-HY-111844-5MG,MCE-HY-111844-1MG
Manufacturer: MedchemExpress
Category: Biochemikalien
PROTAC RAR degrader-1 (Compound 9) is a potent and selective RAR PROTAC Degrader consisting of apoptotic protein inhibitors (IAPs) ligands. IAPs-based degraders are also known as SNIPERs. PROTAC RAR Degrader-1 reduces RARalpha levels in HT1080 cells in a concentration-dependent manner but is blocked by the proteasome inhibitor MG132 (HY-13259). PROTAC RAR Degrader-1 can be used in the study of nuclear receptor-related diseases. (Pink: RAR ligand 1 (HY-111843), Black: Linker (HY-140189), Blue: IAPs Ligand (HY-B0134))[1][2].
Molecular Weight: 917.14
Purity: 97.91
CAS Number: [1351169-27-1]
Formula: C51H72N4O11
Target: PROTACs,RAR/RXR,SNIPERs
Application Notes: MCE Product type: Reference compound