CB1 antagonist 4 (compound 8) is a selective cannabinoid receptor 1 (CB1) inverse agonist with an IC50 of 8.5 nM for human CB1. CB1 antagonist 4 shows selective for CB1 over CB2 receptors (IC50 of 604.9 nM). CB1 antagonist 4 inhibits GTP binding to CB1-overexpressing cell membranes with an EC50 of 18.5 nM[1].
Molecular Weight:
617.51
Purity:
98.00
CAS Number:
[1253641-65-4]
Formula:
C30H25Cl2F3N4OS
Target:
Cannabinoid Receptor
Application Notes:
MCE Product type: Reference compound
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