D-65476 is an inhibitor of type III receptor tyrosine kinase (Flt3). In the absence of IL-3, D-65476 inhibits the proliferation of TEL-Flt3 transfected BA/F3 cells (IC50= 0.2 µM), which can be used in the study of Flt3-driven leukemia[1].
Molecular Weight:
346.38
CAS Number:
[249762-74-1]
Formula:
C21H18N2O3
Target:
FLT3
Application Notes:
MCE Product type: Reference compound
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