F-1 is a potent ALK and ROS1 dual inhibitor, suppresses phospho-ALK and its relative downstream signaling pathways, with IC50s of 2.1 nM, 2.3 nM, 1.3 nM and 3.9 nM for ALKWT, ROS1WT, ALKL1196M and ALKG1202R, respectively[1].
Molecular Weight:
519.02
Purity:
98.03
CAS Number:
[2244775-31-1]
Formula:
C22H27ClN8O3S
Target:
Anaplastic lymphoma kinase (ALK),ROS Kinase
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
