GSK8814, CAS [[1997369-78-4]]

Product Overview

• Article Name: GSK8814, CAS [[1997369-78-4]]
• Biozol Catalog Number: MCE-HY-114204
• Supplier Catalog Number: HY-114204
• Alternative Catalog Number: MCE-HY-114204-5MG,MCE-HY-114204-10MG,MCE-HY-114204-1MG,MCE-HY-114204-10MMX1ML
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GSK8814 is a potent and selective ATAD2 bromodomain chemical probe and inhibitor (IC50 = 0.059 µM), with a binding constant pKd = 8.1 and a pKi = 8.9 in BROMOscan. GSK8814 binds to ATAD2 and BRD4 BD1 with pIC50s of 7.3 and 4.6, respectively. GSK8814 shows 500-fold selectivity for ATAD2 over BRD4 BD1. GSK8814 can be researched for cancer associated with ATAD2 bromodomain[1][2][3].

Product Properties

• Molecular Weight: 527.61
• Purity: 99.80
• CAS Number: [1997369-78-4]
• Formula: C28H35F2N5O3
• Target: Epigenetic Reader Domain

Application Notes

• Application Notes: MCE Product type: Reference compound