ML345, CAS [[1632125-79-1]]

Product Overview

• Article Name: ML345, CAS [[1632125-79-1]]
• Biozol Catalog Number: MCE-HY-117878
• Supplier Catalog Number: HY-117878
• Alternative Catalog Number: MCE-HY-117878-10MG,MCE-HY-117878-50MG,MCE-HY-117878-100MG,MCE-HY-117878-25MG,MCE-HY-117878-10MMX1ML,MCE-HY-117878-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

ML345 is a potent and selective inhibitor of insulin-degrading enzyme (IDE) and NLRP3, with an IC50 of 188 nM against IDE. ML345 targets the Cys819 residue of IDE to inhibit IDE. ML345 selectively binds to NLRP3 in a non-covalent manner. ML345 inhibits inflammatory cytokines (IL-1beta, IL-6) and exhibits potent anti-inflammatory activity. ML345 exerts a protective effect against miscarriage[1][2].

Product Properties

• Molecular Weight: 479.54
• Purity: 99.37
• CAS Number: [1632125-79-1]
• Formula: C21H22FN3O5S2
• Target: IDE,Interleukin Related,NOD-like Receptor (NLR)

Application Notes

• Application Notes: MCE Product type: Reference compound