AKN-028 (acetate)

Product Overview

• Article Name: AKN-028 (acetate)
• Biozol Catalog Number: MCE-HY-118304B
• Supplier Catalog Number: HY-118304B
• Alternative Catalog Number: MCE-HY-118304B-10MG,MCE-HY-118304B-50MG,MCE-HY-118304B-5MG,MCE-HY-118304B-10MMX1ML,MCE-HY-118304B-100MG,MCE-HY-118304B-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AKN-028 acetate, a novel tyrosine kinase (TK) inhibitor, is a potent, orally active FMS-like receptor tyrosine kinase 3 (FLT3) inhibitor with an IC50 value of 6 nM. AKN-028 acetate inhibits FLT3 autophosphorylation. AKN-028 acetate induces dose-dependent cytotoxic response (mean IC50=1 µM). AKN-028 acetate induces apoptosisby activation of caspase 3. AKN-028 acetate can be used in research of acute myeloid leukemia (AML).

Product Properties

• Molecular Weight: 362.39
• Purity: 98.38
• Formula: C19H18N6O2
• Target: Apoptosis,Caspase,FLT3

Application Notes

• Application Notes: MCE Product type: Reference compound