2-Methoxyestradiol-13C6 is the 13C-labeled 2-Methoxyestradiol. 2-Methoxyestradiol (2-ME2), an orally active endogenous metabolite of 17beta-estradiol (E2), is an apoptosis inducer and an angiogenesis inhibitor with potent antineoplastic activity. 2-Methoxyestradiol also destablize microtubules. 2-Methoxyestradio, also a potent superoxide dismutase (SOD) inhibitor and a ROS-generating agent, induces autophagy in the transformed cell line HEK293 and the cancer cell lines U87 and HeLa[1][2][3][4][5][6].
Molecular Weight:
308.36
Formula:
C13 13C6H26O3
Target:
Apoptosis,Autophagy,Endogenous Metabolite,Isotope-Labeled Compounds,Microtubule/Tubulin,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Isotope-Labeled Compounds
* VAT and and shipping costs not included. Errors and price changes excepted
