Genz-669178, CAS [[1254834-91-7]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-120462
Supplier Catalog Number:
HY-120462
Alternative Catalog Number:
MCE-HY-120462-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
Genz-669178 is an inhibitor for dihydroorotate dehydrogenase (DHODH) with IC50 of 0.015-0.05 µM in Plasmodium spp.. Genz-669178 inhibits P. berghei, P. falciparum strains 3D7 and Dd2 with IC50 of 0.068, 0.008 and 0.01 µM, respectively. Genz-669178 exhibits anti-malarial efficacy in P. berghei-infected mice with ED50 of 13-21 mg/kg/day. Genz-669178 exhibits good pharmacokinetic characteristics in mice[1].
Molecular Weight:
322.38
CAS Number:
[1254834-91-7]
Formula:
C17H14N4OS
Target:
Dihydroorotate Dehydrogenase,Parasite
Application Notes:
Reference compound
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