KBU2046, CAS [[1143863-69-7]]

Product Overview

• Article Name: KBU2046, CAS [[1143863-69-7]]
• Biozol Catalog Number: MCE-HY-120548
• Supplier Catalog Number: HY-120548
• Alternative Catalog Number: MCE-HY-120548-25MG,MCE-HY-120548-50MG,MCE-HY-120548-10MMX1ML,MCE-HY-120548-100MG,MCE-HY-120548-5MG,MCE-HY-120548-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

KBU2046 is an orally active transforming growth factor-beta (TGF-beta1) inhibitor. KBU2046 reduces integrin family protein expression, decreases Raf, RIPK1 and ERK phosphorylation to deactivate the ERK signaling pathway, and down-regulates genes linked to TGF-beta1 maturation. KBU2046 suppresses tumor cell motility, impedes cancer invasion and metastasis, and inhibits human ESCC growth and metastasis in a murine model. KBU2046 can be used for the researches of triple-negative breast cancer and esophageal squamous cell carcinoma[1][2].

Product Properties

• Molecular Weight: 242.25
• Purity: 99.52
• CAS Number: [1143863-69-7]
• Formula: C15H11FO2
• Target: ERK,Integrin,Raf,RIP kinase,TGF-beta Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound