CU-3 is a DGKalpha inhibitor with an IC50 of 0.6 µM. CU-3 competitively reduces DGKalphas affinity for ATP via binding to the enzymes catalytic region. CU-3 induces apoptosis in cancer cells. CU-3 promotes T-cell activation and enhances IL-2 production. CU-3 can be used for the research of hepatocellular carcinoma and cervical cancer[1].
Molecular Weight:
392.47
CAS Number:
[2983265-35-4]
Formula:
C16H12N2O4S3
Target:
Apoptosis,Caspase,DGK,Interleukin Related
Application Notes:
MCE Product type: Reference compound
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