Pifithrin-alpha, p-Nitro, Cyclic, CAS [[60477-38-5]]

Product Overview

• Article Name: Pifithrin-alpha, p-Nitro, Cyclic, CAS [[60477-38-5]]
• Biozol Catalog Number: MCE-HY-123076
• Supplier Catalog Number: HY-123076
• Alternative Catalog Number: MCE-HY-123076-50MG,MCE-HY-123076-10MG,MCE-HY-123076-5MG,MCE-HY-123076-100MG,MCE-HY-123076-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: PFN-alpha

Product Description

Pifithrin-alpha, p-Nitro, Cyclic (PFN-alpha) is cell-permeable and active-form p53 inhibitor. Pifithrin-alpha, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-alpha in protecting cortical neurons exposed to Etoposide (ED50=30 nM). Pifithrin-alpha, p-Nitro, Cyclic behaves as a p53 posttranscriptional activity inhibitor. Pifithrin-alpha, p-Nitro, Cyclic do not prevent p53 phosphorylation on the S15 residue[1][2].

Product Properties

• Molecular Weight: 299.35
• Purity: 99.37
• CAS Number: [60477-38-5]
• Formula: C15H13N3O2S
• Target: MDM-2/p53

Application Notes

• Application Notes: Reference compound