Leucrose (5-O-alpha-D-Glucopyranosyl-D-fructose) is an orally active Sucrose (HY-B1779) isomer naturally found in pollen and honey. Leucrose promotes phosphorylation of JAK1 and STAT6, reduces pro-inflammatory mediators and cytokinesas (TNFalpha, and IL-1beta), increases M2 macrophage polarization and suppresses DSS (HY-116282C)-induced colitis. Leucrose suppresses hepatic triglyceride accumulation, improves fasting blood glucose levels, and regulates hepatic lipogenesis and fatty acid beta-oxidation in high-fat diet-induced obese mice. Leucrose is slowly hydrolyzed into glucose and fructose by alpha-glucosidase and acts as as a sugar substitute in diet[1][2][3].
Molecular Weight:
342.30
Purity:
98.53
CAS Number:
[7158-70-5]
Formula:
C12H22O11
Target:
Interleukin Related,JAK,STAT,TNF Receptor
Application Notes:
MCE Product type: Natural Products
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