Lofepramine, CAS [[23047-25-8]]

Catalog Number: MCE-HY-12390
Article Name: Lofepramine, CAS [[23047-25-8]]
Biozol Catalog Number: MCE-HY-12390
Supplier Catalog Number: HY-12390
Alternative Catalog Number: MCE-HY-12390-50MG,MCE-HY-12390-10MG,MCE-HY-12390-5MG,MCE-HY-12390-25MG,MCE-HY-12390-10MMX1ML,MCE-HY-12390-100MG
Manufacturer: MedchemExpress
Category: Biochemikalien
Alternative Names: Lopramine
Lofepramine (Lopramine) is a modified tricyclic and orally active antidepressant. Lofepramine inhibits the uptake of Noradrenaline (NA) (HY-13715) and 5-hydroxytryptamine (5-HT) with IC50s of 2.7 µM and 11 µM, respectively. Lofepramine exerts its antidepressant activity by promoting noradrenergic neurotransmission. Lofepramine also enhances serotonergic neurotransmission by inhibiting neuronal uptake of 5-HT and tryptophan pyrrolase. Lofepramine exhibits significant anxiolytic properties. [1][2][3][4].
Molecular Weight: 418.96
Purity: 99
CAS Number: [23047-25-8]
Formula: C26H27ClN2O
Target: 5-HT Receptor,Adrenergic Receptor
Application Notes: MCE Product type: Reference compound