ZLDI-8, CAS [[667880-38-8]]

Catalog Number: MCE-HY-123931
Article Name: ZLDI-8, CAS [[667880-38-8]]
Biozol Catalog Number: MCE-HY-123931
Supplier Catalog Number: HY-123931
Alternative Catalog Number: MCE-HY-123931-50MG,MCE-HY-123931-100MG,MCE-HY-123931-25MG,MCE-HY-123931-10MMX1ML,MCE-HY-123931-5MG,MCE-HY-123931-10MG
Manufacturer: MedchemExpress
Category: Biochemikalien
ZLDI-8 is a Notch activating/cleaving enzyme ADAM-17 inhibitor and inhibits the cleavage of Notch protein. ZLDI-8 decreases the expression of pro-survival/anti-apoptosis and epithelial-mesenchymal transition (EMT) related proteins. ZLDI-8 is also a competitive and irreversible tyrosine phosphatase (Lyp) inhibitor with an IC50 of 31.6 µM and a Ki of 26.22 µM. ZLDI-8 inhibits the growth of MHCC97-H cells with an IC50 of 5.32 µM[1][2].
Molecular Weight: 433.52
Purity: 98.47
CAS Number: [667880-38-8]
Formula: C24H23N3O3S
Target: Apoptosis,Notch,Phosphatase
Application Notes: Reference compound