Raphin1, CAS [[2022961-17-5]]

Product Overview

• Article Name: Raphin1, CAS [[2022961-17-5]]
• Biozol Catalog Number: MCE-HY-123960
• Supplier Catalog Number: HY-123960
• Alternative Catalog Number: MCE-HY-123960-25MG,MCE-HY-123960-10MG,MCE-HY-123960-10MMX1ML,MCE-HY-123960-50MG,MCE-HY-123960-5MG,MCE-HY-123960-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease[1].

Product Properties

• Molecular Weight: 231.08
• Purity: 99.75
• CAS Number: [2022961-17-5]
• Formula: C8H8Cl2N4
• Target: Phosphatase

Application Notes

• Application Notes: Reference compound