ITI-214 (free base), CAS [[1160521-50-5]]

Product Overview

• Article Name: ITI-214 (free base), CAS [[1160521-50-5]]
• Biozol Catalog Number: MCE-HY-12501
• Supplier Catalog Number: HY-12501
• Alternative Catalog Number: MCE-HY-12501-10MG,MCE-HY-12501-5MG,MCE-HY-12501-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

ITI-214 free base is a potent, CNS-active, orally bioavailable PDE1 inhibitor (Ki of 58 pM) with excellent selectivity against other PDE family members and against a panel of enzymes, receptors, transporters and ion channels. ITI-214 free base inhibits recombinant full-length human PDE1A, PDE1B and PDE1C with Kis of 33 pM, 380 pM and 35 pM, respectively. ITI-214 free base shows efficacy in various animal models of motor and cognitive functions[1][2].

Product Properties

• Molecular Weight: 507.56
• Purity: 98
• CAS Number: [1160521-50-5]
• Formula: C29H26FN7O
• Target: Phosphodiesterase (PDE)

Application Notes

• Application Notes: MCE Product type: Reference compound