TED-347, CAS [[2378626-29-8]]

Product Overview

• Article Name: TED-347, CAS [[2378626-29-8]]
• Biozol Catalog Number: MCE-HY-125269
• Supplier Catalog Number: HY-125269
• Alternative Catalog Number: MCE-HY-125269-50MG,MCE-HY-125269-1MG,MCE-HY-125269-100MG,MCE-HY-125269-5MG,MCE-HY-125269-10MMX1ML,MCE-HY-125269-10MG,MCE-HY-125269-25MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

TED-347 is a potent, irreversible, covalent and allosteric inhibitor at YAP-TEAD protein-protein interaction with an EC50 of 5.9 µM for TEAD4 Yap1 protein-protein interaction. TED-347 specifically and covalently bonds with Cys-367 within the central pocket of TEAD4 with a Ki of 10.3 µM. TED-347 blocks TEAD transcriptional activity and has antitumor activity[1].

Product Properties

• Molecular Weight: 313.70
• Purity: 98.97
• CAS Number: [2378626-29-8]
• Formula: C15H11ClF3NO
• Target: YAP

Application Notes

• Application Notes: MCE Product type: Reference compound1