EGFR mutant-IN-1, a 5-methylpyrimidopyridone derivative, is a potent and selective EGFRL858R/T790M/C797S mutant inhibitor with an IC50 of 27.5 nM, while being a significantly less potent for EGFRWT (IC50 >1.0 µM)[1].
Molecular Weight:
632.17
Formula:
C34H39ClFN7O2
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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