NDI-091143, CAS [[2375840-87-0]]

Product Overview

• Article Name: NDI-091143, CAS [[2375840-87-0]]
• Biozol Catalog Number: MCE-HY-127111
• Supplier Catalog Number: HY-127111
• Alternative Catalog Number: MCE-HY-127111-10MMX1ML,MCE-HY-127111-10MG,MCE-HY-127111-50MG,MCE-HY-127111-25MG,MCE-HY-127111-100MG,MCE-HY-127111-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

NDI-091143 is a potent and high-affinity human ATP-citrate lyase (ACLY) inhibitor with an IC50 of 2.1 nM (ADP-Glo assay), a Ki of 7.0 nM and a Kd of 2.2 nM. NDI-091143 inhibits ACLY catalysis allosterically, by stabilizing large conformational changes in the citrate domain that indirectly block the binding and recognition of citrate[1].

Product Properties

• Molecular Weight: 453.84
• Purity: 99.72
• CAS Number: [2375840-87-0]
• Formula: C20H14ClF2NO5S
• Target: ATP Citrate Lyase

Application Notes

• Application Notes: MCE Product type: Reference compound