Platensimycin is an antibiotic produced by S. platensis that inhibits gram-positive bacteria by selectively inhibiting cellular lipid biosynthesis (IC50=0.1 µM). Platensimycin targets the beta-ketoacyl-acyl-carrier-protein synthase I/II, FabF/B, an enzyme that participates in the biosynthesis of fatty acids (IC50s=48 nM and 160 nM for S.aureus and E.coli enzymes, respectively). Platensimycin is a promising agent for overcoming antibiotic resistance.
Molecular Weight:
441.47
Purity:
95.00
CAS Number:
[835876-32-9]
Formula:
C24H27NO7
Target:
Antibiotic,Bacterial
Application Notes:
MCE Product type: Natural Products
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