5-(N,N-Hexamethylene)-amiloride, CAS [[1428-95-1]]

Product Overview

• Article Name: 5-(N,N-Hexamethylene)-amiloride, CAS [[1428-95-1]]
• Biozol Catalog Number: MCE-HY-128067
• Supplier Catalog Number: HY-128067
• Alternative Catalog Number: MCE-HY-128067-5MG,MCE-HY-128067-50MG,MCE-HY-128067-10MMX1ML,MCE-HY-128067-100MG,MCE-HY-128067-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: Hexamethylene amiloride, HMA

Product Description

5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) derives from an amiloride and is a potent Na+/H+ exchanger inhibitor, which decreases the intracellular pH (pHi) and induces apoptosis in leukemic cells. 5-(N,N-Hexamethylene)-amiloride (Hexamethylene amiloride) is also an inhibitor of the HIV-1 Vpu virus ion channel and inhibits mouse hepatitis virus (MHV) replication and human coronavirus 229E (HCoV229E) replication in cultured L929 cells with EC50s of 3.91 µM and 1.34 µM, respectively[1][2].

Product Properties

• Molecular Weight: 311.77
• Purity: 99.14
• CAS Number: [1428-95-1]
• Formula: C12H18ClN7O
• Target: Apoptosis,HIV,Sodium Channel

Application Notes

• Application Notes: MCE Product type: Reference compound