ARS-1323-alkyne, CAS [[2436544-27-1]]

Product Overview

• Article Name: ARS-1323-alkyne, CAS [[2436544-27-1]]
• Biozol Catalog Number: MCE-HY-128522
• Supplier Catalog Number: HY-128522
• Alternative Catalog Number: MCE-HY-128522-50MG,MCE-HY-128522-5MG,MCE-HY-128522-1MG,MCE-HY-128522-10MMX1ML,MCE-HY-128522-25MG,MCE-HY-128522-100MG,MCE-HY-128522-10MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

ARS-1323-alkyne is a covalent inhibitor probe that covalently binds to the Switch-II pocket (S-IIP) of the KRAS G12C mutant protein. ARS-1323-alkyne visualizes the covalent modification of KRAS G12C and quantitatively measures the binding efficiency of the inhibitor to the target. ARS-1323-alkyne can be used to validate the target occupancy of KRAS G12C inhibitors and the synergistic mechanism of combination therapy[1].

Product Properties

• Molecular Weight: 569.00
• Purity: 99.59
• CAS Number: [2436544-27-1]
• Formula: C28H27ClF2N6O3
• Target: Ras

Application Notes

• Application Notes: MCE Product type: Reference compound