TBK1/IKKepsilon-IN-5 (compound 1) is an orally active TBK1 and IKKepsilon dual inhibitor, with IC50 values of 1 and 5.6 nM, respectively. TBK1/IKKepsilon-IN-5 enhances the blockade response to PD-1 and induces immune memory in rats when combines with anti-PD-L1. TBK1/IKKepsilon-IN-5 can be used in cancer research, especially in tumour immunity[1].
Molecular Weight:
513.59
Purity:
99.96
CAS Number:
[1893397-65-3]
Formula:
C28H31N7O3
Target:
IKK
Application Notes:
MCE Product type: Reference compound
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