Androgen receptor antagonist 1 is an orally available full androgen receptor (AR) antagonist with an IC50 of 59 nM[1]. Androgen receptor antagonist 1 (Compound 6) can be used in the synthesis of PROTAC AR degraders, which results 24% and 47 % AR protein degradation in LNCaP cells at 1 µM and 10 µM, respectively[2].
Molecular Weight:
416.90
Purity:
99.64
CAS Number:
[1338812-36-4]
Formula:
C21H25ClN4O3
Target:
Androgen Receptor,Ligands for Target Protein for PROTAC
Application Notes:
Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted
