I-OMe-Tyrphostin AG 538, CAS [[1094048-77-7]]

Product Overview

• Article Name: I-OMe-Tyrphostin AG 538, CAS [[1094048-77-7]]
• Biozol Catalog Number: MCE-HY-135680
• Supplier Catalog Number: HY-135680
• Alternative Catalog Number: MCE-HY-135680-5MG,MCE-HY-135680-10MG,MCE-HY-135680-25MG,MCE-HY-135680-10MMX1ML,MCE-HY-135680-100MG,MCE-HY-135680-50MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: I-OMe-AG 538

Product Description

I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase alpha (PI5P4Kalpha), with an IC50 of 1 µM[1].

Product Properties

• Molecular Weight: 437.19
• Purity: 98.03
• CAS Number: [1094048-77-7]
• Formula: C17H12INO5
• Target: IGF-1R

Application Notes

• Application Notes: MCE Product type: Reference compound1