Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-gamma production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells[1][2].
Molecular Weight:
556.65
Purity:
99.96
CAS Number:
[59086-90-7]
Formula:
C34H36O7
Target:
Apoptosis,PKC
Application Notes:
MCE Product type: Natural Products
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