BMS-P5 is a selective and orally active peptidylarginine deiminase 4 (PAD4) inhibitor with an IC50 of 98 nM. BMS-P5 shows selective for PAD4 over PAD1, PAD2, and PAD3. BMS-P5 blocks multiple myeloma (MM)-induced neutrophil extracellular trap (NET) formation and delays progression of MM in a syngeneic mouse model[1].
Molecular Weight:
509.04
Purity:
99.23
CAS Number:
[1549811-36-0]
Formula:
C27H33ClN6O2
Target:
Protein Arginine Deiminase
Application Notes:
MCE Product type: Reference compound
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