Lufotrelvir (PF-07304814), a phosphate proagent of PF-00835231, acts as a potent 3CLpro protease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174nM. Lufotrelvir is promising single antiviral agent and also can be used for the research of combination with other antivirals that target other critical stages of the coronavirus life cycle.
Molecular Weight:
552.51
Purity:
99.87
CAS Number:
[2468015-78-1]
Formula:
C24H33N4O9P
Target:
SARS-CoV
Application Notes:
MCE Product type: Reference compound
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