PROTAC BRD4 Degrader-9 (compound 8a) is a PROTAC connected by ligands for von Hippel-Lindau and BRD4. PROTAC BRD4 Degrader-9 can be conjugated with STEAP1 and CLL1 antibodies to degrade the BRD4 protein in PC3 prostate cancer cells, with a DC50 of 0.86 nM and 7.6 nM, respectively[1].
Molecular Weight:
1312.50
Purity:
98.23
CAS Number:
[2417370-42-2]
Formula:
C59H71F2N9O15S4
Target:
Epigenetic Reader Domain,PROTACs
Application Notes:
MCE Product type: ADC Related
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