(Rac)-Vepdegestrant, CAS [[2229711-08-2]] Preis auf Anfrage

Product Overview

• Article Name: (Rac)-Vepdegestrant, CAS [[2229711-08-2]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-138642A
• Supplier Catalog Number: HY-138642A
• Alternative Catalog Number: MCE-HY-138642A-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: (Rac)-ARV-471

Product Description

(Rac)-Vepdegestrant is the isomer of Vepdegestrant (HY-138642). Vepdegestrant ((R)-Lavandulol) is an orally active PROTAC estrogen receptor degrader against breast cancer. Vepdegestrant is a hetero-bifunctional molecule that facilitates the interactions between estrogen receptor alpha and an intracellular E3 ligase complex. Vepdegestrant leads to the ubiquitylation and subsequent degradation of estrogen receptors via the proteasome. Vepdegestrant robustly degrades ER in ER-positive breast cancer cell lines with a half-maximal degradation concentration (DC50) of about 2 nM[1].

Product Properties

• Molecular Weight: 723.90
• CAS Number: [2229711-08-2]
• Formula: C45H49N5O4
• Target: Estrogen Receptor/ERR,PROTACs

Application Notes

• Application Notes: MCE Product type: Reference compound