AK-778-XXMU, CAS [[1227045-76-2]]

Product Overview

• Article Name: AK-778-XXMU, CAS [[1227045-76-2]]
• Biozol Catalog Number: MCE-HY-144707
• Supplier Catalog Number: HY-144707
• Alternative Catalog Number: MCE-HY-144707-100MG,MCE-HY-144707-25MG,MCE-HY-144707-50MG,MCE-HY-144707-10MMX1ML,MCE-HY-144707-10MG,MCE-HY-144707-5MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AK-778-XXMU is a potent DNA binding inhibitor 2 (ID2) antagonist with a KD of 129 nM. AK-778-XXMU can inhibit cell migration and invasion of glioma cell lines, induce apoptosis, and exhibits significant cancer-suppressing potency. AK-778-XXMU inhibits the ID2-KDR signaling axis, thereby down-regulating the downstream angiogenic factors (VEGFA) and invasion-related proteins (MMP2/9), and up-regulating the tumor suppressor factor (PTEN). AK-778-XXMU can be used for the study of glioma[1].

Product Properties

• Molecular Weight: 392.83
• Purity: 99.96
• CAS Number: [1227045-76-2]
• Formula: C22H17ClN2O3
• Target: Apoptosis,MMP,PTEN,VEGFR

Application Notes

• Application Notes: Reference compound